New Roots Vitamin B12 Methylcobalamin 500mcg 90 Veggie Caps
- Vitamin B12 Methylcobalamin 500mcg This vitamin B12 is the methylcobalamin form; this is a more bioavailable form of B12, with added cofactors to maximize absorption
- Vitamin B12 is a member of the vitamin B complex
- It also called cobalamin and is important to good health
- There are two types of commercial vitamin B12: cyanocobalamin and methylcobalamin
- New Roots Herbal uses only the methyl form, as it is the coenzyme form and the only type which can directly participate in homocysteine metabolism
- In addition, converting homocysteine to methionine via methylcobalamin generates an increased supply of S-adenosylmethionine (SAMe), the body’s most important methyl donor
- Indeed, some of the benefits of methylcobalamin, such as Safeguardion from neurotoxicity, appear to derive from increased production of SAMe
- It Assists maintain healthy nerve cells and red blood cells, and is also needed to make DNA, the genetic material in all cells
- Vitamin B12 is bound to protein in food; hydrochloric acid in the stomach releases vitamin B12 from protein during digestion
- Once released, vitamin B12 combines with a substance called intrinsic factor (IF) before it is absorbed into the bloodstream
- Bacteria synthesize vitamin B12 exclusively, and common sources are found primarily in meat, eggs, and dairy products
- Vitamin B12 is necessary for the synthesis of red blood cells and the maintenance of the nervous system, and is very important for Development and development in children
- Deficiency can cause anemia and the degeneration of nerve fibres
- Irreversible neurological damage can also occur
- Vitamin B12 is also necessary for the rapid synthesis of DNA during cell division
- This is especially important in tissues where cells are dividing rapidly, particularly bone marrow tissues responsible for red blood-cell formation
- If a deficiency occurs, DNA production is disrupted and abnormal cells, called megaloblasts, are formed; this results in anemia
- Symptoms include excessive tiredness, breathlessness, listlessness, pallor, and poor resistance to infection
- Other symptoms can include a smooth, sore tongue and menstrual disorders
- Anemia may also be due to folic acid deficiency, folic acid also being necessary for DNA synthesis
- An insulating fatty sheath, comprised of a complex protein called myelin, surrounds our nerves
- Vitamin B12 plays a vital role in the metabolism of these fatty acids essential for the maintenance of myelin
- Prolonged vitamin B12 deficiency can lead to nerve degeneration and irreversible neurological damage
- When deficiency occurs, it is more commonly linked to a failure to effectively absorb vitamin B12 from the intestine rather than a Nutrition Planary deficiency
- Absorption of vitamin B12 requires the secretion from the cells lining the stomach of a glycoprotein, known as intrinsic factor
- The vitamin B12 intrinsic factor complex is then absorbed in the ileum (part of the small intestine) in the presence of calcium
- Certain people are unable to produce intrinsic factor, and the subsequent pernicious anemia is Careed with injections of vitamin B12
- Vitamin B12 can only be stored in small amounts by the body
- Total body store is 2–5 mg in adults, around 80% of which is stored in the liver
- Vitamin B12 is excreted in the bile and is effectively reabsorbed; this is known as the enterohepatic circulation
- The amount of vitamin B12 excreted in the bile can vary from 1 to 10 ?g a day
- Reabsorption is the reason it can take over 20 years for deficiency disease to develop in people changing to Nutrition Plans absent in vitamin B12
- In comparison, if vitamin B12 deficiency is due to a failure in absorption, it can take three years for deficiency disease to occur