- Grape Seed Extract 500mg The proanthocyanidin-rich formula safeguards sensitive tissues and organ systems in the body against disease-causing free radicals
- Grape seed extract, a bioflavonoid abundant in proanthocyanidins, serves the purpose of combating free radicals and supporting capillary health
- Its resemblance to pine bark extract lies in its high proanthocyanidin content
- Free radicals inflict damage on capillaries through two mechanisms: Inactivating a compound called 1-antitripsin, responsible for restraining enzymes that break down collagen, elastin, and hyaluronic acid
- Turning the fats in cell membranes rancid through lipid peroxidation
- Proanthocyanidins play a protective role by neutralizing specific types of free radicals that pose a threat to 1-antitripsin and lipids
- They may also directly inhibit damaging enzymes
- Collagen, elastin, and hyaluronic acid constitute a significant portion of the inner wall and supporting matrix of capillaries
- When these components are in good condition, capillaries stretch to allow red blood cells through tight spaces while preventing fluid leakage
- Proanthocyanidins exhibit a notable tendency to accumulate in tissues rich in glycosaminoglycans, such as capillary walls and skin, possibly extending to cartilage and synovial fluid
- At high concentrations (250 ?g/ml), they show antimutagenic effects in vitro
- Proanthocyanidins, also known as leucoanthocyanidins and pycnogenols, belong to the polyphenol family, a type of bioflavonoid
- They surpass vitamin E by at least 15 to 25 times in neutralizing iron and reactive oxygen species/free radicals attacking lipids
- Grape seed extract is utilized for its ability to combat free radicals and address various conditions linked to capillary health and permeability
- It synergizes with vitamin C, enhancing its potency and rapid absorption when used in conjunction with proanthocyanidins
- Proanthocyanidins in grape seeds demonstrate anti-inflammatory, antiarthritic, and antiallergic activities
- They contribute to preventing skin aging, scavenging oxygen free radicals, and inhibiting the damaging effects of UV radiation from sunlight
- Furthermore, they form bonds with collagen, a crucial protein in the body found in skin, gums, bones, teeth, hair, and other tissues
- Proanthocyanidins are recommended for conditions such as poor distribution of microcirculatory blood flow in the brain and Cardio Health, altered capillary fragility and permeability (in diabetes mellitus), chronic arterial/venous insufficiency in the extremities, altered platelet aggregation, breakdown in the elastic fibers of capillaries due to free-radical and enzyme action, microangiopathy of the retina, edema of the lymph nodes, varicose veins, cumulative effects of aging, and reducing the risk of degenerative diseases
